Alu insertion lab report

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"Alu insertion lab report"에 대한 내용입니다.

목차

1. Abstract
2. Introduction
3. Methods
4. Result
5. Discussion

본문내용

Abstract
The PV92 Alu insertion is a polymorphic marker located on chromosome 16 within an intron. And it is widely studied for its significance in population genetics. In this experiment, we examined the frequency of the PV92 Alu insertion in a group of 7 students using polymerase chain reaction (PCR), gel electrophoresis, and BLAST analysis. The observed genotype frequencies were compared with expected genotype frequencies under Hardy-Weinberg equilibrium with a Chi-square test. Results indicated that 5 students have the Alu insertion, among them, 2 students have a heterozygous allele. A Chi-square value of 1.21 and a p-value of 0.2719 indicated no significant difference between observed and expected frequencies. Further analysis using BioServer data showed that the + allele (with Alu insertion) is more prevalent in Asian and South American populations, while the – allele is more common in Africa and Europe. This suggesting that the role of genetic drift and human migration.

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