[A+] Report 3-hexylthiophene through work-up and purification (3-hexylthiophene 추출 레포트)

소개

"Report 3-hexylthiophene through work-up and purification (3-hexylthiophene 추출 레포트)"에 대한 내용입니다.

목차

1. Introduction
1) Purpose of the Experiment
2) Theoretical Background

2. Method
1)Materials by experiment
2)Procedures and Experimental Set-up

3. Result & Discussion

4. Conclusion

본문내용

- Purpose of the Experiment
To obtain 3-hexylthiophene through work-up and purification from reaction mixture synthesized using 3-bromothiophene, hexylmagnesium bromide, Ni catalyst, and THF.

- Theoretical Background
1.Work-up
Work-up means the manipulation necessary to separate and purify the product of a chemical reaction. Examples include quenching, cooling, liquid-liquid extraction, evaporation, separation, and chromatography.

2.Thin-Layer Chromatography(TLC) / Column Chromatography
TLC is a chromatography technique used to determine components of non-volatile mixtures using a thin stationary phase supported by inert backing. It uses the speed difference from the difference in attraction to the stationary phase and the difference in solubility of the solvent.
Column Chromatography method is used to separate a single substance from a mixture.

참고자료

· Wade, L. G., & Simek, J. W. (2017). Organic chemistry (9th ed.). Glenview, IL: Pearson.
· Harwood, L. M., & Moody, C. J. (1996). Experimental organic chemistry: Principles and practice. Australia: Blackwell Science.
· Stevenson, A., & Lindberg, C. (2010). The New Oxford American Dictionary (3rd ed.). Oxford: Oxford University Press.
· Sherma, J., & Fried, B. (2003). Handbook of thin-layer chromatography. New York: Marcel Dekker.
· Smith, M. B. (2019), Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (8th ed.), New York: Wiley
· Corriu, R. J. P. & Masse, J. P. (1972, January 1). "Activation of Grignard reagents by transition-metal complexes. A new and simple synthesis of trans-stilbenes and polyphenyls". Journal of the Chemical Society, Chemical Communications (3): 144a. doi:10.1039/C3972000144A