쥐를 대상으로 한 산화 스트레스와 근육 발달 연구에서 동일 강도의 자발적 운동과 강제적 운동의 효과 차이 연구 (Different Effects on Oxidative Stress & Muscle Development of Rats through Voluntary or Involuntary Exercise with the Same Intensity)

서지정보

· 발행기관 : 한국생활환경학회
· 수록지 정보 : 한국생활환경학회지 / 24권 / 2호 / 163 ~ 170페이지
· 저자명 : 최근훈, 장래근, 송영주, 정유진, 윤정원, 박현

초록

The aim of this study is to clarify the physiological effects from these two different ways of aerobicexercise methods in various parameters. Thirty male rats(20 wks old) completed 6 wks of exercise. The wheel exercisewas performed with counting of rotations then their total working distance(apprx 400 m/day) was applied same totreadmill exercise. To measure the oxidative stress level, rats were decapitated right after the daily exercise bout. Plasmasamples were used for determination of Reactive Oxygen Metabolites(d-ROMs) and Biological Antioxidant Potential(BAP) test. To compare muscle properties, we extracted five muscles(soleus, plantaris, Extensor Digitorum Longus(EDL), Flexor Hallucis Longus(FHL), Tibialis Anterior(TA)) and then measured each muscle weight and the enzymeactivity of Citrate Synthase(CS), especially in plantaris. There was no significant difference in d-ROMs test, however,in the BAP test, treadmill and wheel groups showed higher value than control group(p<.05). There were no significantdifferences in muscle weight. In CS activity, both exercise groups showed significant increase, but no significant differencebetween these two groups(p<.05). Wheel group showed the highest value between groups. Even though mostof results showed no significant difference, the pattern in muscles morphology, oxidative stress, and aerobic exercisecapacity may show slight difference. From these results, we have to consider the difference between ways of exerciseaccording to the target variables and the purpose of research properly.

영어초록

The aim of this study is to clarify the physiological effects from these two different ways of aerobicexercise methods in various parameters. Thirty male rats(20 wks old) completed 6 wks of exercise. The wheel exercisewas performed with counting of rotations then their total working distance(apprx 400 m/day) was applied same totreadmill exercise. To measure the oxidative stress level, rats were decapitated right after the daily exercise bout. Plasmasamples were used for determination of Reactive Oxygen Metabolites(d-ROMs) and Biological Antioxidant Potential(BAP) test. To compare muscle properties, we extracted five muscles(soleus, plantaris, Extensor Digitorum Longus(EDL), Flexor Hallucis Longus(FHL), Tibialis Anterior(TA)) and then measured each muscle weight and the enzymeactivity of Citrate Synthase(CS), especially in plantaris. There was no significant difference in d-ROMs test, however,in the BAP test, treadmill and wheel groups showed higher value than control group(p<.05). There were no significantdifferences in muscle weight. In CS activity, both exercise groups showed significant increase, but no significant differencebetween these two groups(p<.05). Wheel group showed the highest value between groups. Even though mostof results showed no significant difference, the pattern in muscles morphology, oxidative stress, and aerobic exercisecapacity may show slight difference. From these results, we have to consider the difference between ways of exerciseaccording to the target variables and the purpose of research properly.

참고자료

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