SLA 처리 티타늄 표면에서의 유전자발현에 대한 상온대기압 플라즈마의 효과 (Effects of non-thermal atmospheric pressure air plasma on gene expression at SLA- treated titanium surfaces)

서지정보

· 발행기관 : 대한치과재료학회
· 수록지 정보 : 대한치과재료학회지 / 42권 / 1호 / 15 ~ 20페이지
· 저자명 : 서혜연, 강민경, 권재성, 최은하, 최유리, 김경남

초록

Dental implants manufacturers have developed high hydrophilic and rough implant surfaces which in turn exhibited better osseointegration than conventional ones. Based on in vitro studies, sand blast, large grit, acid etching(SLA)-treated surfaces with microstructural characteristics may promote the process of osseointegration. But when the SLA surface is kept dry in the air, it becomes hydrophobic. Appropriate non-thermal atmospheric pressure air plasma jet(air-NTAPPJ) processes render surfaces hydrophilic. The purpose of this research is to air-NTAPPJ on SLA surface treatment to improve the osteogenic functionality. The experiment was carried out through the a cytotoxicity assay and real-time reverse transcriptase-polymerase chain reaction(RT-PCR). The results were that the cell viability and gene expression of ALP, OCN, OPN, and Runx-2 of rMSC enhanced by air-NTAPPJ treated. Thus, air-NTAPPJ application can lead to an improved osseointegration.

영어초록

Dental implants manufacturers have developed high hydrophilic and rough implant surfaces which in turn exhibited better osseointegration than conventional ones. Based on in vitro studies, sand blast, large grit, acid etching(SLA)-treated surfaces with microstructural characteristics may promote the process of osseointegration. But when the SLA surface is kept dry in the air, it becomes hydrophobic. Appropriate non-thermal atmospheric pressure air plasma jet(air-NTAPPJ) processes render surfaces hydrophilic. The purpose of this research is to air-NTAPPJ on SLA surface treatment to improve the osteogenic functionality. The experiment was carried out through the a cytotoxicity assay and real-time reverse transcriptase-polymerase chain reaction(RT-PCR). The results were that the cell viability and gene expression of ALP, OCN, OPN, and Runx-2 of rMSC enhanced by air-NTAPPJ treated. Thus, air-NTAPPJ application can lead to an improved osseointegration.

참고자료

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