기능성 소화불량증에서 위장관 미주신경 활성 평가를 위한 심박변이지표와 장음지표의 상관성 연구 (Correlation Between HRV And Bowel Sound Parameters in The Evaluation of Gastrointestinal Parasympathetic Nerve Activity from Patients with Functional Dyspepsia)

서지정보

· 발행기관 : 대한한방내과학회
· 수록지 정보 : 대한한방내과학회지 / 30권 / 1호 / 173 ~ 180페이지
· 저자명 : 김소연, 윤상협

초록

Objectives : The aim of this study was to investigate the evaluation of gastrointestinal parasympathetic nerve activity by comparing between HRV and bowel sound parameters in patient with functional dyspepsia.
Methods : 62 patients(male 22, female 40) were enrolled. HRV was measured in all patients, and TP(Total Power), LF(Low Frequency Density0.04∼0.15Hz), HF(High Frequency Density; 0.15∼0.4Hz), and LF/HF ratio were analyzed. HF band is a reflection of parasympathetic activity, and the LF-to-HF ratio is considered a marker of sympathovagal balance. Bowel sounds were recorded at the day after, and postprandial %BS were used to indicate the gastric vagal activity after eating. HRV and Bowel sound parameters were compared, and correlation between them was analyzed.
Results : There was no difference in LF/HF ratio between patient group and healthy group of other report. According to values of %BS, each patient was classified into normal(>6 %BS) or hypoactivity(<6 %BS) of gastric vagus nerve group. HF component of hypoactivity group was not significantly higher than normal group. There was no correlation between HRV and Bowel sound parameters.
Conclusions : Because no correlation was found between HRV and Bowel sound parameters in patients with functional dyspepsia, we concluded that it is not proper to evaluate gastric vagus nerve activity by HRV measurement.

영어초록

Objectives : The aim of this study was to investigate the evaluation of gastrointestinal parasympathetic nerve activity by comparing between HRV and bowel sound parameters in patient with functional dyspepsia.
Methods : 62 patients(male 22, female 40) were enrolled. HRV was measured in all patients, and TP(Total Power), LF(Low Frequency Density0.04∼0.15Hz), HF(High Frequency Density; 0.15∼0.4Hz), and LF/HF ratio were analyzed. HF band is a reflection of parasympathetic activity, and the LF-to-HF ratio is considered a marker of sympathovagal balance. Bowel sounds were recorded at the day after, and postprandial %BS were used to indicate the gastric vagal activity after eating. HRV and Bowel sound parameters were compared, and correlation between them was analyzed.
Results : There was no difference in LF/HF ratio between patient group and healthy group of other report. According to values of %BS, each patient was classified into normal(>6 %BS) or hypoactivity(<6 %BS) of gastric vagus nerve group. HF component of hypoactivity group was not significantly higher than normal group. There was no correlation between HRV and Bowel sound parameters.
Conclusions : Because no correlation was found between HRV and Bowel sound parameters in patients with functional dyspepsia, we concluded that it is not proper to evaluate gastric vagus nerve activity by HRV measurement.

참고자료

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