neuronal loss is difficult 1. density of neuronal profiles is modified by size of cells, overestimated ... hyperphosphorylation - dephosphorylation rapidly occurs after deathDisease Protein/marker Topography PD ... bodies Loss of neurons, synpses , astrocytosis – non-specific lesions Accumulation of proteins in the
prevent it from freezing.c) digestion by Hind3Fig2.modified oligo(dT)- Cellulose chromathography(2 step ... method). 1st step elution profile without heating of TPA and PHA-P-stimulated lymphocytes total RNA ... The peak ; not retained by the columnchromatographyFig.3.Modified oligo(dT)-cellulose chromatography(2