소포 림프종에 동반된 강직성 척추염 1예 (A Case of Ankylosing Spondylitis with Follicular Lymphoma)

서지정보

· 발행기관 : 대한류마티스학회
· 수록지 정보 : 대한류마티스학회지 / 18권 / 4호 / 315 ~ 319페이지
· 저자명 : 박희진, 박윤혜, 박경혜, 김미현, 최은영, 한정우, 홍지영, 장명희, 김선정, 심주은, 기정혜, 이상원, 박용범, 이수곤, 이찬희

초록

강직성 척추염은 류마티스관절염처럼 만성적인 염증성관절 질환이지만 이전 연구들에서 강직성 척추염은 다른자가면역 질환과 달리 림프종의 발생률을 의미 있게 증가시키지는 않는 것으로 보고되었다. 국내에서 비호지킨 림프종과 강직성 척추염이 함께 발병한 증례가 보고된 적이 없어, 비호지킨 림프종의 일종인 소포림프종으로 치료 중강직성 척추염이 진단되어 비스테로이드성 진통소염제를사용해서 증상이 호전된 증례를 경험하여 문헌 고찰과 함께 보고하는 바이다.

영어초록

Several autoimmune and chronic inflammatory conditions have been consistently linked with an increased risk of hematologic malignancies. Although ankylosing spondylitis (AS) is a chronic inflammatory disease, previous studies have demonstrated that it is not associated with an increase in risk of malignant lymphomas. Cases of AS accompanied by hematologic malignancies such as multiple myeloma, chronic myelogenous leukemia, and Hodgkin’s disease have been reported. In Korea, AS with non- Hodgkin’s lymphoma or follicular lymphoma has not been reported. We experienced a 38-year-old male who had been diagnosed with follicular lymphoma with bone metastasis, who achieved complete remission after having been treated with chemotherapy, developed new inflammatory back pain. An MRI of his hip showed an active inflammation of the left sacroiliac joint and a positive HLA-B27. The patient was diagnosed with AS and was treated with naproxen, which improved the pain in his back and buttock.

참고자료

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