체계적 고찰/메타분석 연구 비판적으로 바라보기 (Critical Appraisal of Systematic Review/Meta-analysis)

서지정보

· 발행기관 : 대한상부위장관ㆍ헬리코박터학회
· 수록지 정보 : Korean Journal of Helicobacter Upper Gastrointestinal Research / 15권 / 2호 / 73 ~ 79페이지
· 저자명 : 김현정, 안형식

초록

In recent years, the number of systematic review and meta-analysis literatures has markedly increased. Systematic reviews can give important information about clinical decision making when studies show different or even contradictory results. By utilizing systematic reviews, clinicians can get unbiased summaries of the estimates, which are a reliable source of clinical information. Contrary to the narrative review, the systematic review conducts a comprehensive research of relevant studies on a defined clinical question, and critically appraises the risk of bias in included studies. The systematic review usually includes meta-analysis which summarizes the quantitative estimates by using statistical methods. Most meta-analyses aggregate data from primary studies, but individual data are also commonly used. Explaining heterogeneity among included studies and subsequent subgroup analysis are often required. Systematic review and meta-analysis depend on the quality of included studies, and subsequently cannot overcome the limitations of primary studies. Also, meta-analysis is prone to publication biases and methodological flaws. Despite these limitations, systematic review has definitive strengths. Maximizing these strengths require reliable second-hand data and a comprehensive analysis

영어초록

In recent years, the number of systematic review and meta-analysis literatures has markedly increased. Systematic reviews can give important information about clinical decision making when studies show different or even contradictory results. By utilizing systematic reviews, clinicians can get unbiased summaries of the estimates, which are a reliable source of clinical information. Contrary to the narrative review, the systematic review conducts a comprehensive research of relevant studies on a defined clinical question, and critically appraises the risk of bias in included studies. The systematic review usually includes meta-analysis which summarizes the quantitative estimates by using statistical methods. Most meta-analyses aggregate data from primary studies, but individual data are also commonly used. Explaining heterogeneity among included studies and subsequent subgroup analysis are often required. Systematic review and meta-analysis depend on the quality of included studies, and subsequently cannot overcome the limitations of primary studies. Also, meta-analysis is prone to publication biases and methodological flaws. Despite these limitations, systematic review has definitive strengths. Maximizing these strengths require reliable second-hand data and a comprehensive analysis

참고자료

· 없음