해조류 복합추출물을 이용한 마스크팩 임상시험 연구 (A Clinical Trial of Facial Mask using Seaweed Complex Extracts)

서지정보

· 발행기관 : 대한통합의학회
· 수록지 정보 : 대한통합의학회지 / 13권 / 1호 / 159 ~ 170페이지
· 저자명 : 윤현서, 박충무

초록

Purpose : This study tried to analyze the functionalities of seaweed complex extract as functional cosmetics including four kinds of brown algae which are known for their skin whitening and skim moisturizing activities.
Methods : Then, they were evaluated as the source of functional cosmetics. The bioavailability of seaweed complex extracts was evaluated by cytotoxicity, anti-inflammatory, and antioxidative activities. Based on these results, the prototype of the face sheet mask was prepared and the safety was verified by a certified accreditation institute. After IRB approval (DIRB—202109-HR-R-16) at University D, a clinical trial was conducted on 60 participants and the results of 57 people were analyzed after excluding dropouts. Before and after participation, the skin was measured using a professional skin measuring instrument SDM, and the personal hydrometer was used to measure the center of the cheeks twice a week.
Results : Participants in the clinical trial tended to prefer moisture cosmetics over others, purchase skin whitening cosmetics mainly in summer. After the clinical trial, the skin moisture was increased to 9.8 in the experimental group. In addition, the degree of oiliness and pore change was also the most potently regulated in the experimental group. Otherwise, the elasticity was strongly regulated in the control group C. In the results of the personal hydrometer, the degree of skin moisture was the highest in the experimental group, and the degree of oiliness was significantly modulated in both experimental and control group C.
Conclusion : The prototype of a face sheet mask using seaweed complex extracts showed the most potent change in skin moisture, improved pores, and elasticity, as well as improved skin brightness, blemishes, and dryness. Consequently, these results show the potential of seaweed complex extract to be used as an ingredient in functional cosmetics.

영어초록

Purpose : This study tried to analyze the functionalities of seaweed complex extract as functional cosmetics including four kinds of brown algae which are known for their skin whitening and skim moisturizing activities.
Methods : Then, they were evaluated as the source of functional cosmetics. The bioavailability of seaweed complex extracts was evaluated by cytotoxicity, anti-inflammatory, and antioxidative activities. Based on these results, the prototype of the facial mask was prepared and the safety was verified by a certified accreditation institute. Then, the prototype was compared with three commercially available products as control groups. After IRB approval (DIRB—202109-HR-R-16) at university D, a clinical trial was conducted on 60 participants and the results of 57 people were analyzed after excluding dropouts. Before and after participation, the skin was measured using a professional skin measuring instrument SDM, and the personal hydrometer was used to measure the center of the cheeks twice a week.
Result : Participants in the clinical trial tended to prefer moisture cosmetics over others, show more interests in moisturizing ones at over 70%, and purchase skin whitening cosmetics mainly in summer. After the clinical trial, the skin moisture was increased to 9.8 in the experimental group. In addition, the degree of oiliness and pore change was also the most potently regulated in the experimental group. Otherwise, the elasticity was strongly regulated in the control group C. In the results of the personal hydrometer, the degree of skin moisture was the highest in the experimental group, and the degree of oiliness was significantly modulated in both experimental and control group C. After a result of the survey, the experimental group scored 4.4 points for ‘this facial mask feels skin brighter than the others’, and scored the highest points for ‘this product relieves dryness and reduces blemishes’.
Conclusion : The prototype of a facial mask using seaweed complex extracts showed the most potent change in skin moisture, improved pores, and elasticity, as well as improved skin brightness, blemishes, and dryness. Consequently, these results show the potential of seaweed complex extract to be used as an ingredient in functional cosmetics.

참고자료

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