삽살개의 연령에 따른 혈구 및 혈청 생화학 수치 변화 양상 연구 (Changes in the complete blood count and serum biochemical parameters of Sapsaree dogs according to different age groups)

서지정보

· 발행기관 : 한국동물위생학회
· 수록지 정보 : 한국동물위생학회지 / 42권 / 4호 / 227 ~ 236페이지
· 저자명 : 이승원, 김은주, 오상익, 하지홍, 이부근, 류재규, 도윤정

초록

The complete blood count and serum biochemical parameters are essential tools for diagnosis and mon-itoring of physiological and disease conditions in dogs. These parameters may be affected by the breed and age of dogs. This study aimed to compare the changes of complete blood count and serum biochemical parameters according to the increasing age in 156 Sapsarees. In this study, the Sapsarees were clustered into ten age groups: four to six months, seven to nine months, ten to twelve months, one year, two years, three to four years, five to six years, seven to eight years, nine to ten years, and, eleven to twelve years old. In the result of the complete blood count, the total red blood cell count (P＜0.001), hematocrit (P＜ 0.001), and hemoglobin (P＜0.001) values were significantly increased from 4∼6 months to 2 years old Sapsarees. While the mean corpuscular volume (P＜0.001) and mean corpuscular hemoglobin (P＜ 0.001) values were significantly increased from 4∼6 months to 3∼4 years old. The mean corpuscular hemoglobin concentration was significantly (P=0.037) increased from 4∼6 to 10∼12-month-old Sap-sarees. Total white cell count was significantly (P＜0.001) decreased from 1 year to 9∼10 years old. The result of differential white blood cell count showed that neutrophil count was significantly (P＜ 0.001) increased from the age 4∼6 months to 11∼12 years old Sapsarees, whereas, lymphocyte (P＜ 0.001), monocyte (P＜0.001), and eosinophil (P=0.042) counts were significantly decreased from 7∼9 months to 7∼8 years, 4∼6 months to 9∼10 years, 3∼4 to 5∼6 years old, respectively. In the serum bio-chemistry result, the creatinine concentration was significantly (P＜0.001) increased from 4∼6 to 10∼12 months, but significantly (P=0.006) decreased from 7∼8 to 10∼12 years old. Phosphate concentration was significantly (P＜0.001) decreased from 3∼4 to 9∼10 years old, but significantly (P=0.021) increased from 9∼10 to 11∼12 years old. Calcium concentration significantly (P＜0.001) decreased from 10∼12 months to 11∼12 years old. Total protein concentration significantly (P＜0.001) increased from 4∼6 months to 2 years old. While concentrations of albumin (P=0.004) and globulin (P＜0.001) was signifi-cantly increased from 4∼6 months to 3∼4 years old, and from 4∼6 months to 11∼12 years old, respect-ively. The alkaline phosphate concentration was significantly (P＜0.001) decreased from 4∼6 months to 2 years old. We found that there are differences in the hematological parameters in relation with the increasing age in Sapsaree breed.

영어초록

The complete blood count and serum biochemical parameters are essential tools for diagnosis and mon-itoring of physiological and disease conditions in dogs. These parameters may be affected by the breed and age of dogs. This study aimed to compare the changes of complete blood count and serum biochemical parameters according to the increasing age in 156 Sapsarees. In this study, the Sapsarees were clustered into ten age groups: four to six months, seven to nine months, ten to twelve months, one year, two years, three to four years, five to six years, seven to eight years, nine to ten years, and, eleven to twelve years old. In the result of the complete blood count, the total red blood cell count (P＜0.001), hematocrit (P＜ 0.001), and hemoglobin (P＜0.001) values were significantly increased from 4∼6 months to 2 years old Sapsarees. While the mean corpuscular volume (P＜0.001) and mean corpuscular hemoglobin (P＜ 0.001) values were significantly increased from 4∼6 months to 3∼4 years old. The mean corpuscular hemoglobin concentration was significantly (P=0.037) increased from 4∼6 to 10∼12-month-old Sap-sarees. Total white cell count was significantly (P＜0.001) decreased from 1 year to 9∼10 years old. The result of differential white blood cell count showed that neutrophil count was significantly (P＜ 0.001) increased from the age 4∼6 months to 11∼12 years old Sapsarees, whereas, lymphocyte (P＜ 0.001), monocyte (P＜0.001), and eosinophil (P=0.042) counts were significantly decreased from 7∼9 months to 7∼8 years, 4∼6 months to 9∼10 years, 3∼4 to 5∼6 years old, respectively. In the serum bio-chemistry result, the creatinine concentration was significantly (P＜0.001) increased from 4∼6 to 10∼12 months, but significantly (P=0.006) decreased from 7∼8 to 10∼12 years old. Phosphate concentration was significantly (P＜0.001) decreased from 3∼4 to 9∼10 years old, but significantly (P=0.021) increased from 9∼10 to 11∼12 years old. Calcium concentration significantly (P＜0.001) decreased from 10∼12 months to 11∼12 years old. Total protein concentration significantly (P＜0.001) increased from 4∼6 months to 2 years old. While concentrations of albumin (P=0.004) and globulin (P＜0.001) was signifi-cantly increased from 4∼6 months to 3∼4 years old, and from 4∼6 months to 11∼12 years old, respect-ively. The alkaline phosphate concentration was significantly (P＜0.001) decreased from 4∼6 months to 2 years old. We found that there are differences in the hematological parameters in relation with the increasing age in Sapsaree breed.

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