일개 제빵회사 근로자의 제빵공 천식 유병률 (Prevalence of Baker’s Asthma among Workers in an Industrial Bakery)

서지정보

· 발행기관 : 대한직업환경의학회
· 수록지 정보 : Annals of Occupational and Environmental Medicine / 20권 / 3호 / 245 ~ 259페이지
· 저자명 : 김정민, 주영수, 임형준, 이태경, 강혜련, 백도명, 권영준

초록

Objectives: To determine the prevalence of baker’s asthma due to flour dust in an industrial bakery in
Korea.
Methods: Of the 596 active workers, 380 were allocated to a category of either direct exposure (DE)
or indirect exposure (IE) to flour dust and completed a modified ISAAC questionnaire. Of the 380 participants,
233 were screened by an occupational physician interview, a skin prick test, and an ELISA for
serum-specific IgE antibodies to wheat flour extracts. Selected workers received serial monitoring of
peak expiratory flow rate (PEFR), and positive PEFR respondents received a methacholine challenge
test. The diagnosis of baker’s asthma was confirmed by a specific inhalation challenge with wheat flour
extracts.
Results: The prevalence of sensitization to wheat flour and baker’s asthma was 21.0% (25.9% DE,
13.3% IE) and 3.2% (5.1% DE, 1.8% IE), respectively. DE had an increased risk of sensitization to wheat
flour (OR 2.15, 95% CI = 1.03~4.51). Sensitization to wheat flour and the prevalence of baker’s asthma
correlated significantly (PR 38.63, 95% CI = 6.14~243.22).
Conclusions: These findings indicate a considerable prevalence of baker’s asthma among flourexposed
workers in Korea. Future studies will be required to survey the situation in flour mill companies
and seek ways to protect the health and socioeconomic position of flour industry workers.

영어초록

Objectives: To determine the prevalence of baker’s asthma due to flour dust in an industrial bakery in
Korea.
Methods: Of the 596 active workers, 380 were allocated to a category of either direct exposure (DE)
or indirect exposure (IE) to flour dust and completed a modified ISAAC questionnaire. Of the 380 participants,
233 were screened by an occupational physician interview, a skin prick test, and an ELISA for
serum-specific IgE antibodies to wheat flour extracts. Selected workers received serial monitoring of
peak expiratory flow rate (PEFR), and positive PEFR respondents received a methacholine challenge
test. The diagnosis of baker’s asthma was confirmed by a specific inhalation challenge with wheat flour
extracts.
Results: The prevalence of sensitization to wheat flour and baker’s asthma was 21.0% (25.9% DE,
13.3% IE) and 3.2% (5.1% DE, 1.8% IE), respectively. DE had an increased risk of sensitization to wheat
flour (OR 2.15, 95% CI = 1.03~4.51). Sensitization to wheat flour and the prevalence of baker’s asthma
correlated significantly (PR 38.63, 95% CI = 6.14~243.22).
Conclusions: These findings indicate a considerable prevalence of baker’s asthma among flourexposed
workers in Korea. Future studies will be required to survey the situation in flour mill companies
and seek ways to protect the health and socioeconomic position of flour industry workers.

참고자료

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